Obstructive sleep apnea may induce orexinergic system and cerebral β-amyloid metabolism dysregulation: is it a further proof for Alzheimer's disease risk?

Is Apnea-Hypopnea Index a proper measure for Obstructive Sleep Apnea severity?

Obstructive sleep apnea and the severity of coronary artery disease

Background: It has been implicated that obstructive sleep apnea (OSA) is associated with increased risk of cardiovascular disease including stroke, myocardial infarction, coronary artery disease (CAD) and hypertension. The aim of this study was to investigate the correlation between OSA and severity of atherosclerosis assessed by angiography. Methods: This study included 337 patients ...

Is it mild obstructive sleep apnea?

A 63-year-old woman was referred to the sleep center complaining of daytime sleepiness, snoring, and insomnia. She was single and never married but, on a recent business trip, was noted by a colleague to snore loudly. There was no report of witnessed apnea. She slept 8 to 8.5 hours per night but complained of daytime drowsiness and mental fogginess, particularly in the afternoons. She occasiona...

Serum amyloid a in obstructive sleep apnea.

BACKGROUND Patients with severe obstructive sleep apnea (OSA) may have increased risk for cardiovascular and cerebrovascular diseases. Serum amyloid A (SAA) protein has recently been linked to the development of atherosclerosis, stroke, diabetes, and dementia. We tested the hypothesis that plasma SAA levels are increased in otherwise healthy subjects with OSA. METHODS AND RESULTS Plasma SAA l...

Determination of The Relationship Between Severity of Obstructive Sleep Apnea And Chronic Obstructive Pulmonary Disease

Introduction: Chronic obstructive pulmonary disease (COPD) patients are at increased risk of sleep-disorders. The concomitant occurrence of COPD and obstructive sleep apnea hypopnea syndrome (OSAHS) is named overlap syndrome. This study aimed to evaluate the severity of OSAHS in overlap syndrome patients.Materials & Methods: This cross-sectional study was conducted on adult patients with forced...